NINA PIPALIA, PHD
Nina received her Ph.D. from Loyola University, Chicago. Her research in the Maxfield lab focuses neurodegenerative diseases like Niemann-Pick type C1 (NPC1) and Alzheimer’s disease. She has expertise in high throughput/ high content screening (HTS/HCS) and assay development. She works on drug discovery and has conducted small molecule screen to identify drug candidate to treat NPC1 disease. Her findings on HDACi as a potential therapeutic agent has resulted in the small limited patient clinical trial at NIH. She has also conducted genome-wide RNAi screen to identify genes involved in cholesterol metabolism. She has and is collaborating on various different projects including stem cell research, Alzheimer’s disease, and Carbon nanotubes as a diagnostic tool for lipid metabolism-related diseases. Nina received her BS in Chemistry and MS in Organic Chemistry Major and Analytical Chemistry Minor from Mumbai University (India).
RAJESH SINGH, PHD
Rajesh received his Ph.D. in Molecular Medicine from the National Heart and Lung Institute at Imperial College London in November 2011. The focus of his work in the Maxfield Lab is how low-density lipoprotein (LDL) initiates inflammation in the arteries and how macrophages digest LDL during atherosclerosis. He was awarded an American Heart Association and Stanley Stahl Research Fellowship in 2015, and has made significant progress on this work. This has resulted in several research publications, and discovery of many proteins that cause digestion of LDL during atherosclerosis.